PEP4LEP - Chemoprophylaxis for Leprosy Post- Exposure

Is a study that aims to contribute to interrupting the transmission of M. leprae by identifying the most effective and feasible method of screening people at risk of developing leprosy and administering chemoprophylaxis in Ethiopia, Mozambique and Tanzania

In 3 years- 2019 to 2021, through an implementation trial, the project will compare the effectiveness and feasibility of a skin camp intervention to a health centre-based intervention. The purpose of the research project is to provide chemoprophylaxis in the form of Single Dose (SDR) Rifampicin to contacts of leprosy patients in order to reduce their risk of developing leprosy in 60%.

In Mozambique, the project is being implemented in Nampula Province (Meconta, Murrupula, Mogovolas Districts), through a partnership composed by NLR Mozambique, Ministry of Health (Provincial Health Directorate) and Universidade Lúrio.

This study will contribute towards the achievement of the United Nations’ Sustainable Development Goal 3: ‘Ensure healthy lives and promote well-being for all at all ages’ by generating evidence for the most effective and feasible way to integrate chemoprophylaxis for leprosy into routine leprosy control programmes in different socio-cultural settings in sub-Saharan Africa.

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